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We studied childhood cancer incidence in a population-based twin cohort using record linkage to the National Registry of Childhood Tumours. After correcting for mortality, an incidence deficit was observed (Standardized Incidence Ratio (SIR) 79; 95% Confidence Interval (CI) 39-120). Pooled analysis with data from published cohort studies indicates a similar significant incidence reduction (SIR 81, 95% CI 67-96). Further studies are warranted.

Original publication

DOI

10.1054/bjoc.2001.1799

Type

Journal article

Journal

Br J Cancer

Publication Date

01/06/2001

Volume

84

Pages

1460 - 1462

Keywords

Child, Child Welfare, Child, Preschool, Cohort Studies, England, Female, Humans, Incidence, Infant, Infant, Newborn, Male, Neoplasms, Registries