Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

There is a substantial body of epidemiological and clinical evidence suggesting that the sex hormones, particularly estradiol and progesterone, play a role in pain. Behavioral studies have not been useful in understanding the relationship between sex hormones and pain perception, and certainly have not helped to elucidate the mechanisms by which such effects may be mediated. This review aims to address the additional insights functional imaging has given us into the role of sex hormones in pain. Functional imaging techniques and experimental designs are discussed before the literature investigating specific questions relating to hormones and pain is reviewed. Finally, we conclude by considering how results of studies imaging the influence of sex hormones in related areas such as emotion and cognition also may inform our understanding of this complex area.

Original publication

DOI

10.1007/s11916-010-0139-1

Type

Journal article

Journal

Curr Pain Headache Rep

Publication Date

10/2010

Volume

14

Pages

396 - 403

Keywords

Animals, Evidence-Based Medicine, Female, Gonadal Steroid Hormones, Humans, Magnetic Resonance Imaging, Male, Menstrual Cycle, Pain, Positron-Emission Tomography