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A donor who was highly reactive to diphtheria toxoid (DT) in delayed hypersensitivity and in lymphocyte transformation showed scant evidence of antigen-induced inhibition in the direct leucocyte migration agarose test. Other donors, weak or negative to DT in skin test and transformation, did show evidence of inhibition. Although the migration test is useful in assessing cellular reactivity to tubercular antigen, these results question its suitability for DT.

Type

Journal article

Journal

Allergy

Publication Date

08/1987

Volume

42

Pages

473 - 476

Keywords

Adult, Cell Migration Inhibition, Diphtheria Toxoid, Humans, Hypersensitivity, Delayed, Leukocyte Migration-Inhibitory Factors, Leukocytes, Lymphocyte Activation, Male, Tuberculin Test