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BACKGROUND: There is increasing evidence that serum lipids and apolipoproteins may be associated with multiple sclerosis (MS) clinical course. OBJECTIVE: To investigate the associations between serum lipids, apolipoproteins, body mass index and relapse in MS. METHODS: A prospective cohort of 141 participants with relapsing-remitting MS was followed from 2002 to 2005. Serum lipid and apolipoprotein levels were measured biannually, and body mass index at baseline. The association with hazard of relapse was assessed using survival analysis. RESULTS: Neither body mass index nor any of the lipid-related measures were associated with the hazard of relapse. CONCLUSION: Serum lipid profile and body mass index are not associated with the hazard of relapse in MS.

Original publication

DOI

10.1016/j.jns.2014.02.038

Type

Journal article

Journal

J Neurol Sci

Publication Date

15/05/2014

Volume

340

Pages

230 - 232

Keywords

Apolipoprotein, Cholesterol, Lipid, Multiple sclerosis, Profile, Relapse, Apolipoproteins, Body Mass Index, Cohort Studies, Disability Evaluation, Female, Humans, Lipids, Male, Multiple Sclerosis, Observation, Proportional Hazards Models, Recurrence, Risk