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Sex differences in the prevalence of painful conditions appear after pubertyVariation in symptom severity across the menstrual cycle occurs in a number of clinical pain conditionsSex steroid hormones act at a number of sites in both the peripheral and central nervous systems and in both reproductive and non-reproductive tissuesSex steroid hormones have traditionally been thought to alter transcription; however, there is evidence that there are also non-genomic effectsSex steroid hormones can have organisational effects from as early as in uteroThe relationship between sex hormones and pain is complex.

Original publication

DOI

10.1177/204946370800200206

Type

Journal article

Journal

Rev Pain

Publication Date

12/2008

Volume

2

Pages

20 - 24