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The aim of the present study was to analyse the expression of 60 pro-inflammatory cytokines as possible markers of malignancy in canine mammary tumours using a human cytokine antibody array. The cytokines were grouped into two different categories: (1) cytokines in which expression indicated the presence of a mammary tumour and (2) cytokines in which expression differentiated between simple mammary adenoma, tubulopapillary carcinoma or complex carcinoma. These data suggest that specific pro-inflammatory cytokines could be useful as tools for the diagnosis of canine mammary tumours.

Original publication

DOI

10.1016/j.tvjl.2016.01.016

Type

Journal article

Journal

Vet J

Publication Date

04/2016

Volume

210

Pages

92 - 94

Keywords

Canine mammary gland, Complex carcinoma, Pro-inflammatory cytokines, Simple adenoma, Tubulopapillary carcinoma