After two years of undergraduate training at the Semmelweis University in Budapest I studied medicine at the Freie Universität Berlin and briefly at the University of California San Francisco. In 1998 I received my MD from Berlin. I began my residency in obstetrics and gynaecology at the Charité Berlin in 1996 and received my full registration in 2003. During this time and again afterwards I spend a total of five years as a postdoctoral fellow jointly at Children's Hospital and Brigham and Women's Hospital Harvard Medical School in Boston. Under the guidance of Judah Folkman I began working on angiogenesis and antiangiogenic therapy first in various cancer models and later in endometriosis. In late 2005 I joined the Nuffield Department of Obstetrics and Gynaeology in Oxford first as a Clinical Fellow and then as a Clinical Lecturer and Subspecialist Trainee in Reproductive Medicine and Surgery. In 2009 I became a Senior Lecturer in Reproductive Medicine and a Honorary Consultant Gynaecologist at the Women's Centre of the John Radcliffe Hospital in Oxford. Recently, I was appointed as Associate Professor.
I was recently appointed as Chairperson of the Guideline Development Group of the ESHRE (European Society for Human Reproduction and Embryology) Guideline for the Management of Women with Endometriosis. This guideline has been adopted by many national gynaecological societies such as the Royal College of Obstetricians and Gynaecologists. Together with Krina Zondervan (NDOG), Stacey Missmer (Harvard University) and Lone Hummelshoj (World Endometriosis Research Foundation) I head EPHect (Endometriosis Phenome and Biobanking Harmonisation Project), which has produced the current standards in data and sample collection and processing for endometriosis research.
Phone: +44 1865 221622
Phone: +44 1865 782874
Fax: +44 1865 595223
Christian M. Becker
Associate Professor, Co-Director Endometriosis CaRe Centre
- Principal Investigator
- Consultant Gynaecologist & Subspecialist in Reproductive Medicine
- Lead Oxford BSGE Endometriosis Centre
- Lead Adolescent Gynaecology
My research as well as my clinical work focuses on endometriosis, a common disease in women mostly of reproductive age, which is associated with abdominal pain and subfertility. Together with Krina Zondervan I direct the Oxford Endometriosis CaRe Centre, a unique approach to combine excellent and compassionate clinical care with cutting-edge, collaborative research in endometriosis. As Clinical Lead for the Oxford BSGE Endometriosis Centre, one of the largest tertiary referral centres in the UK, I have the great opportunity to work together with a wonderful team of highly dedicated nurses, doctors, and administrators with the aim to improve the situation for many women and their partners affected by the disease. I am very grateful that many women chose to donate biological samples and share their clinical history with us which enables us to do basic and translational research studies for a change in the future.
Current Research Studies:
- Identification of potential biomarkers of endometriosis
- Improving the categorisation of endometriosis
- Target discovery leading to novel, more individualised management
Current Clinical Studies:
- PRE-EMPT Trial (Preventing Recurrence of Endometriosis by Means of long acting Progestogen Therapy; local PI)
- EndOx Study (Biorepository of anonymised biological samples and clinical data from women with endometriosis and controls); Co-PI with Krina Zondervan)
- ENDOPAIN Study (Identifying predictors of response to surgical treatment of endometriosis-associated pain; Co-PI with Katy Vincent)
Carol Hubbard, Maryjane Dale, Lisa Buck
Phone: +44 1865 220011
Phone: +44 1865 5772258
Toward operative in vivo fluorescence imaging of the c-Met proto-oncogene for personalization of therapy in ovarian cancer.
Liu S. et al, (2015), Cancer, 121, 202 - 213
Reevaluating response and failure of medical treatment of endometriosis: a systematic review.
Becker CM. et al, (2017), Fertil Steril, 108, 125 - 136
Top ten endometriosis research priorities in the UK and Ireland
Horne AW. et al, (2017), The Lancet, 389, 2191 - 2192
Meta-analysis identifies five novel loci associated with endometriosis highlighting key genes involved in hormone metabolism.
Sapkota Y. et al, (2017), Nat Commun, 8
The management of menopause in women with a history of endometriosis: a systematic review.
Gemmell LC. et al, (2017), Human Reproduction Update, 23, 481 - 500
Genome-wide genetic analyses highlight mitogen-activated protein kinase (MAPK) signaling in the pathogenesis of endometriosis.
Uimari O. et al, (2017), Hum Reprod, 32, 780 - 793
Preventing recurrence of endometriosis by means of long-Acting progestogen therapy (PRE-EMPT): Report of an internal pilot, multi-arm, randomised controlled trial incorporating flexible entry design and adaption of design based on feasibility of recruitment
Middleton LJ. et al, (2017), Trials, 18
MARKERS OF ESTEEM
- Chair ESHRE Guideline Development Group Endometriosis
- Expert Witness for NICE Endometriosis Guideline Development Group
- Steering Group Member of Priority Setting Partnership for Endometriosis, The James Lind Alliance
- Steering Committee Member, UCON Trial
- Oxford Reproductive Medicine Subspecialty Training Programme Supervisor
- Lead Gynaecological Surgeon for Oxford Ovarian Cryopreservation Service
- WERF EPHect Core Group Member
- Endometriosis UK Medical Advisory Panel
- Organiser RCOG Course: Science for Subspecialties
- Grant Reviewer for multiple national and international councils
- Reviewer for multiple peer-reviewed medical journals
- Editorial Board Current Angiogenesis
- Reviewer NHS Map of Medicine for Endometriosis
- Consultant of the Year (2010), Women’s Centre, John Radcliffe Hospital, Oxford
- Teacher of the Month (2009), Year 5 Medical Students, University of Oxford