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BSc (Hons) PhD
Postdoctoral Teaching Fellow
I completed a BSc with first class honours (2003) at the University of Adelaide followed by a Masters in Medial Science (2006) in Obstetrics and Gynaecology, supervised by Dr Robert Gilchrist and Prof David Armstrong, investigating the role of oocyte secreted factors using a mouse model. In 2007 I moved to the Nuffield Department of Obstetrics and Gynaecology to take charge of the flow cytometry facility in Prof Ian Sargent and Prof Chris Redman’s laboratory. During this time I obtained my Ph.D. (2011) in which I focused on characterising blood-derived microvesicles and exosomes in normal pregnancy and pre-eclampsia, using a range of techniques including flow cytometry and pioneered the use of Nanoparticle Tracking Analysis (NTA) for this purpose.
After completing my Ph.D. I continued to work in the same laboratory as a post-doctoral researcher/flow cytometer operator and I also took on the role as deputy laboratory manager. For the past three years, I have worked closely with Dr Dionne Tannetta to isolate, fractionate and characterise human placental syncytiotrophoblast microvesicles and exosomes in normal pregnancy and pre-eclampsia using a dual placental perfusion model. I am also working together with Dr Ingrid Granne to investigate the role of human follicular fluid microvesicles and exosomes in fertility.
- Characterisation of placental syncytiotrophoblast extracellular vesicles in normal pregnancy and pre-eclampsia
- Roles of follicular fluid extracellular vesicles in fertility
Isolation of syncytiotrophoblast microvesicles and exosomes and their characterisation by multicolour flow cytometry and fluorescence Nanoparticle Tracking Analysis.
Dragovic RA. et al, (2015), Methods, 87, 64 - 74
UK–Russia Researcher Links Workshop: extracellular vesicles – mechanisms of biogenesis and roles in disease pathogenesis, M.V. Lomonosov Moscow State University, Moscow, Russia, 1–5 March 2015
Kapustin AN. et al, (2015), Journal of Extracellular Vesicles, 4, 28094 - 28094
Multicolor flow cytometry and nanoparticle tracking analysis of extracellular vesicles in the plasma of normal pregnant and pre-eclamptic women.
Dragovic RA. et al, (2013), Biol Reprod, 89
A study of hepatocyte ischaemia-reperfusion injury and steatosis in a human liver stem cell model
Sivathondan PC. et al, (2013), BRITISH JOURNAL OF SURGERY, 100, 23 - 23
Extracellular vesicle sizing and enumeration by nanoparticle tracking analysis.
Gardiner C. et al, (2013), J Extracell Vesicles, 2